The Trail Blazers will seek a hardship exemption from the NBA after center Joel Przybilla suffered a major knee injury on Tuesday night.
Przybilla ruptured the right patella tendon and also suffered a dislocated patella in Portland's game against Dallas.
The hardship exemption would allow the team to sign another player, but they must wait until Przybilla has missed three games.
The Blazers already received one hardship exemption, which they used to sign Anthony Tolliver as a temporary player.
Only eight of Portland's 15 players with guaranteed contracts were healthy enough to play on Wednesday night.