Bobby Brown scored 41 points in Siena's 98-92 comeback win over Fenerbahce Ulker on Friday.
Brown's 41 points tied Alphonso Ford (2001) and Kaspars Kambala (2002) for the most ever scored in a single Euroleague game.
The previous high for a Top-16 Euroleague game was set by Sarunas Jasikevicius in 2004 with 37.
Brown went 12-for-18 from the floor and 13-for-13 from the line.