C.J. McCollum suffered a fracture of his fifth metatarsal in his left foot.
McCollum, who is one of the top seniors in the country and a projected first round pick in the 2013 NBA Draft, is expected to miss eight to 10 weeks.
"We are going to make sure C.J. is fully recovered and will place the highest priority on quality of care and be certain the injury has healed properly before full activity is resumed," Lehigh head coach Brett Reed said.