At 2-1 odds, the Duke Blue Devils enter the NCAA tournament as the heaviest favorites since the Kentucky Wildcats in 2014-15. The Wildcats lost in the Final Four after going undefeated throughout that season.

More money was bet on Duke to win the title this season than any other team in the country.

At 12-1, Virginia winning the title represents the worst case scenario for casinos.

"Virginia is really the only bomb we're facing," said MGM vice president of risk Jay Rood.