The defending champions beat last season's runners-up in a 111-90 blowout. It was the Pistons' sixth straight and 11th in 12 games, was their second lopsided win over the Lakers in two weeks. They beat them by 22 points at Detroit on Feb. 10.
Tayshaun Prince scored 26 points, Chauncey Billups added 23, and the Pistons never trailed in the rematch, same as in the previous meeting.
Richard Hamilton had 18 points and eight assists, Rasheed Wallace had 19 points, and Ben Wallace had 13 rebounds for the Pistons.
``We played great. We shared the ball, we took care of the ball,'' Detroit coach Larry Brown said. ``We defended well, got out on the break. It was a great team effort.''