James Harden will sit out Sunday night's game against the New Orleans Pelicans with a sprained toe.
It is the first game he'll miss this season.
"He probably could [play], but given the circumstances it's better that he doesn't. He's banged up a little bit," said Mike D'Antoni.
Russell Westbrook will also miss the game due to rest.
The Rockets are 8-6 without Harden in the last 3 seasons.