Kawhi Leonard and Paul George have been ruled out for Friday's home game against the Denver Nuggets.
Ty Lue said that he has no timetable for either player's return.
Leonard is currently recovering from a sprained ankle, with George missing his third game with a right hamstring strain.
Both Leonard and George reportedly worked out and underwent treatment on Wednesday, according to ESPN's Malika Andrews.
Leonard is expected to be reevaluated in the next few days.